The VMO is also known as the teardrop, the much-coveted quad muscle located right above the kneecap. To attack your VMO with the leg press, assume a close stance and place your feet slightly lower on the platform. These should be done when your legs are pumped so do plenty of warm-up sets to load blood in there.
The goal is to develop a ton of metabolic stress, so all sets will be performed like a piston and for a high number of reps. Do a couple of 25-rep sets to get up to your working weight. Drive up hard out of the bottom and get into a rhythm – just pump the weight up and down. Don't lock out. If you hit 25 reps, go up 25 or 45 pounds per side. Keep going until you just miss 25 reps.
To make this even better (or worse depending on how much you enjoy pain), superset the leg presses with partial leg extensions. The leg extension gets a bad rap among lifters and while it isn't a great mass building movement, it's very effective when supersetted with a meat and potatoes lift like the leg press.
Ramp up with several warm-up sets to get your knees ready and then do the following rep scheme: 20, 15, 10, and 8 reps, going progressively heavier each set. Only work the bottom half of the movement, and lean back in the seat!
"What's the point? No one will see my quads anyway,". You just missed the point. Looking good for appearances or for competitions is one thing, but great bodybuilding is more than that. It has to be more than that, or you just don't get it.